Research Article
Aloe Schweinfurthii Gel in the Safe Preservation of Living Periodontal Cells
Mengong Moneboulou Hortense Perpetue*
,
Ekobena Jean Emmanuel,
Ekono Effa Francky,
Nnanga Nga Emmanuel,
Bengondo Messanga C.,
Aka Louka Kattie
Issue:
Volume 11, Issue 1, June 2025
Pages:
1-13
Received:
7 January 2025
Accepted:
24 January 2025
Published:
6 March 2025
DOI:
10.11648/j.ijcoms.20251101.11
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Abstract: Introduction: To address the public health challenges related to the preservation of expelled immature permanent teeth, we have pushed our research towards alternative plant-based media. Plants have always been vital to humanity. This is the case of Aloe which is known for its great diversity with different biological activities. The species chosen for our study is Aloe schweinfurthii. The purpose of the survey was to conduct research on cost-to-dose, accessibility, efficacy and safety. Our overall goal was to evaluate the toxicity of Aloe schweinfurthii gel in order to safely ensure the survival of periodontal ligament cells from an expelled immature permanent tooth. Methods: This experimental study involved acute and subacute toxicity. We evaluated its effects on the weight parameters of the animals, liver, kidney and hematological as well as the histopathology of the organs. Statistical analyses were done by SPSS version 23.0. The tests performed were ANOVA, Student and Newman-Keuls. The values of p <0.05 were considered statistically significant in all tests. The figures were made by Graph pad prism version 8.0.1. Results: The administered A. schweinfurthii did not cause any animal death, nor did they show any obvious sign of toxicity. Weight gain in rats in acute and subacute toxicity was observed. A decrease in liver, lung and brain weight was noted. We noted also an increase in the rate of ALAT, ASAT, serum creatinine, serum uric acid, white blood cells at satellite doses. Histopathology of the organs showed no cellular disorganization, nor damage to the hepatic and renal tissues. Preservation of cellular vitality was observed at all minimum concentrations from 24 to 72 hours in complete safety. Conclusion: Acute and subacute toxicity tests were unremarkable. A. schweinfurthii gel appears to be a good medium for the safe preservation of periodontal ligament cells.
Abstract: Introduction: To address the public health challenges related to the preservation of expelled immature permanent teeth, we have pushed our research towards alternative plant-based media. Plants have always been vital to humanity. This is the case of Aloe which is known for its great diversity with different biological activities. The species chosen...
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Research Article
A Prospective Clinical Study on Transgingival Lag Screws for Management of Dentoalveolar Fractures
Issue:
Volume 11, Issue 1, June 2025
Pages:
14-20
Received:
10 March 2025
Accepted:
25 March 2025
Published:
14 April 2025
Abstract: Dentoalveolar fracture (DAF) is a common injury which comprises of alveolar fractures which include 2-8% of facial fractures. Traditional methods of management of these fractures may not be feasible all the time. The aim of this study is to evaluate the efficiency of transgingival lag screws (TGLS) in management of dentoalveolar fractures. 20 patients with dentoalveolar fractures, either isolated or concomitant with other facial fractures were included in the study. All patients were treated using transgingival lagscrews under local or general anaesthesia and were evaluated for stability, reduction, bone loss, periodontal health and functional rehabilitation with a follow up period of 3 months. All the subjects healed without any complications. The screws were retrieved by the end of 3rd month. A descriptive statistical analysis was done for the assessed parameters. Good fracture stability was noted in 90% of the cases in immediate post operative period. Anatomical reduction assessed radiographically was ideal. Sound periodontal health was maintained effortlessly, inversely reflecting on minimal bone loss. Rehabilitative period was minimal with preinjury average bite force establishment by the end of 3 months. The study concluded that TGLS is an effective alternative to achieve reduction and stabilization in management of dentoalveolar fractures without jeopardizing the blood supply.
Abstract: Dentoalveolar fracture (DAF) is a common injury which comprises of alveolar fractures which include 2-8% of facial fractures. Traditional methods of management of these fractures may not be feasible all the time. The aim of this study is to evaluate the efficiency of transgingival lag screws (TGLS) in management of dentoalveolar fractures. 20 patie...
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